The biggest live debate of the UK's EU referendum campaign is under way at Wembley Arena.
Both sides of the debate are facing questions, starting with the economy, before a 6,000-strong audience.
The BBC's Great Debate represents a final chance for the two sides to get their points across on primetime TV before polls open on Thursday.
Panellists include Boris Johnson, for Leave, and his successor as London Mayor Sadiq Khan, for Remain.
The debate, hosted by David Dimbleby, Mishal Husain and Emily Maitlis, is live on BBC One.
Questions have been grouped into three categories: The economy, immigration and Britain's place in the world, and the audience has been split into Leave and Remain sides.
The Leave campaign is represented by Mr Johnson, Labour MP Gisela Stuart and energy minister Andrea Leadsom, and for Remain the lineup is Mr Khan, Scottish Conservative leader Ruth Davidson, and Frances O'Grady, general secretary of the Trades Union Congress.
Responding to the opening question from a small business owner, Ms Davidson said she knew people found the EU "frustrating and fussy", but said it provided "a level playing field" for small businesses. She said if the UK leaves, the rest of the EU would impose tariffs and taxes.
She read out previous quotes on job losses from key Leave figures including Mr Johnson, who hit back by saying the Remain campaign was "back to Project Fear".
He said it was "extraordinary" to suggest tariffs would be imposed on the UK, saying Germany would be "insane" to do so.
Responding to a question about workers' rights, Ms Leadsom, for Leave, said the UK had led the way on workers' rights, not the EU. "We do not need unelected, bureaucratic European leaders to tell us what our workers rights can be."
Ms O'Grady said EU "red tape" really meant "getting rid of workers' rights".
PA
There will be contributions by campaigners from other political parties, business and journalism on a second, smaller stage.
Among them are former Sainsbury's chief executive Justin King, who backs remaining in the EU, and founder and chairman of Wetherspoons Tim Martin, who supports Brexit.
EU Referendum: The Great Debate will be broadcast on Tuesday 21 June from 20:00 - 22:00 BST (19:00 - 21:00 GMT) on BBC One, on BBC Online and BBC World News. It will be available to watch afterwards on the BBC iPlayer.
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